Publication
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Jaeseong Hwang+, Dae-yeol Ye+, Gyoo Yeol Jung*, Sungho Jang*. Mobile genetic element-based gene editing and genome engineering: recent advances and applications.
Biotechnology Advances 72, 108343 (* corresponding authors)
https://doi.org/10.1016/j.biotechadv.2024.108343 -
Changhwan Hong+, Yoojin Kim+, Hyunjin Lee, Saebom Yun, Hyun Gyu Lim, Jina Yang*, Sungho Jang*. Vibrio species as next-generation chassis for accelerated synthetic biology. (2024) Biotechnology and Bioprocess Engineering (+ co-first authors, * corresponding authors)
https://doi.org/10.1007/s12257-024-00023-7 -
Jeongho Lee, Hyeonmi Shin, Kang Hyun Lee, Hyeseon Lee, Giwon Lee, Sungho Jang, Gyoo Yeol Jung, Hah Young Yoo*, Chulhwan Park*. Component analysis and utilization strategy of brown macroalgae as promising feedstock for sugar platform-based marine biorefinery. (2024) Biotechnology and Bioprocess Engineering (* corresponding authors)
https://doi.org/10.1007/s12257-024-00022-8 -
HG Hwang, A Milito, J-S Yang*, S Jang*, GY Jung*. Riboswitch-guided chalcone synthase engineering and metabolic flux optimization for enhanced production of flavonoids. (2023) Metabolic Engineering 75, 143-152 (* corresponding authors)
https://doi.org/10.1016/j.ymben.2022.12.006 -
Y Xiu, N Zhang, P Prabhakaran, S Jang, Q Yuan, CM Breneman, GY Jung, W Vongsangnak, MAG Koffas. Parallel screening and cheminformatics modeling of flavonoid activated aptasensors. (2022) Synthetic and Systems Biotechnology 7(4), 1148-1158
https://doi.org/10.1016/j.synbio.2022.07.006 -
MB Kim, S Hwangbo, S Jang, YK Jo. Bioengineered Co-culture of organoids to recapitulate host-microbe interactions. (2022) Materials Today Bio 16, 10034
https://doi.org/10.1016/j.mtbio.2022.100345 -
M Kim, S Jang, GY Jung. Development of synthetic riboswitches to guide the evolution of metabolite production in microorganisms. (2022) Methods in Molecular Biology
https://doi.org/10.1007/978-1-0716-2421-0_9 -
HG Hwang, MH Noh, MAG Koffas, S Jang*, GY Jung*. Multi-level rebalancing of the naringenin pathway using riboswitch-guided high-throughput screening. (2021) Metabolic Engineering 67, 417-427 (* corresponding authors)
https://doi.org/10.1016/j.ymben.2021.08.003 -
H Lee, W Kim, S Jang, M-J Seo. Anti-Obesity and Anti-Inflammatory Effects of the Desalted Salicornia europaea L. Fermented by Bacillus velezensis K26. (2021) Food Engineering Progress 25(3), 169-177
http://db.koreascholar.com/article.aspx?code=409474 -
Y Hwang*, SG Kim*, S Jang*, J Kim, GY Jung. Signal amplification and optimization of riboswitch-based hybrid inputs by modular and titratable toehold switches. (2021) Journal of Biological Engineering 15, 11 (* co-first authors)
https://doi.org/10.1186/s13036-021-00261-w -
CH Woo*, S Jang*, G Shin, GY Jung, JW Lee. Sensitive fluorescence detection of SARS-CoV-2 RNA in clinical samples via one-pot isothermal ligation and transcription. (2020) Nature Biomedical Engineering 4(12), 1168-1179 (* co-first authors)
https://doi.org/10.1038/s41551-020-00617-5
~2019
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S Jang*, M Kim*, J Hwang, GY Jung. Tools and systems for evolutionary engineering of biomolecules and microorganisms. (2019) J. Ind. Microbiol. Biotechnol. 46, 1313–1326 (* co-first authors)
https://doi.org/10.1007/s10295-019-02191-5 -
S Jang*, S Jang*, D-K Im, TJ Kang, M-K Oh, GY Jung. Artificial caprolactam-specific riboswitch as an intracellular metabolite sensor. (2019) ACS Synth. Biol. 8(6), 1276-1283 (* co-first authors)
https://doi.org/10.1021/acssynbio.8b00452 -
E-J Seo, CW Kang, J-M Woo, S Jang, YJ Yeon, GY Jung, J-B Park. Multi-level engineering of the Baeyer-Villiger monooxygenase-based Escherichia coli biocatalysts for the production of C9 chemicals from oleic acid. (2019) Metab. Eng. 54, 137-144
https://doi.org/10.1016/j.ymben.2019.03.012 -
S Jang, HG Lim, J Yang, SW Seo, GY Jung. Synthetic regulatory tools to engineer microbial cell factories for chemical production. (2019) Curr. Dev. Biotechnol. (Book title: Synthetic biology, cell engineering and bioprocessing technologies, ISBN: 978-0-444-64085-7) pp. 115-141 (Book Chapter)
https://doi.org/10.1016/B978-0-444-64085-7.00005-8 -
S Jang*, S Jang*, MH Noh, HG Lim, GY Jung. Novel hybrid input part using riboswitch and transcriptional repressor for signal inverting amplifier. (2018) ACS Synth. Biol. 7(9), 2199-2204 (* co-first authors)
https://doi.org/10.1021/acssynbio.8b00213 -
SG Kim, MH Noh, HG Lim, S Jang, S Jang, GY Jung. Molecular parts and genetic circuits for metabolic engineering of microorganisms. (2018) FEMS Microbiol. Lett. 365(17), fny187
https://doi.org/10.1093/femsle/fny187 -
S Jang, S Jang, GY Jung. Toward tunable dynamic repression using CRISPRi. (2018) Biotechnol. J. 1800152 (Commentary)
https://doi.org/10.1002/biot.201800152 -
HG Lim*, S Jang*, S Jang, SW Seo, GY Jung. Design and optimization of genetically encoded biosensors for high-throughput screening of chemicals. (2018) Curr. Opin. Biotechnol. 54, 18-25 (* co-first authors)
https://doi.org/10.1016/j.copbio.2018.01.011 -
S Jang, S Jang, J Yang, SW Seo, GY Jung. RNA-based dynamic genetic controllers: development strategies and applications. (2018) Curr. Opin. Biotechnol. 53, 1-11
https://doi.org/10.1016/j.copbio.2017.10.005 -
S Jang, GY Jung. Systematic optimization of L-tryptophan riboswitches for efficient monitoring of the metabolite in Escherichia coli. (2018) Biotechnol. Bioeng. 115(1), 266-271
https://doi.org/10.1002/bit.26448 -
SG Kim*, S Jang*, JH Lim, BS Jeon, J Kim, KH Kim, B-I Sang, GY Jung. Optimization of hexanoic acid production in recombinant Escherichia coli by precise flux rebalancing. (2018) Bioresour. Technol. 247, 1253-1257 (* co-first authors)
https://doi.org/10.1016/j.biortech.2017.10.014 -
S Jang*, S, Jang*, Y Xiu, TJ Kang, S-H Lee, MAG Koffas, GY Jung. Development of artificial riboswitches for monitoring of naringenin in vivo. (2017) ACS Synth. Biol. 6(11), 2077-2085 (* co-first authors)
https://doi.org/10.1021/acssynbio.7b00128 -
J Sung, S Kim, JJT Cabatbat, S Jang, Y-S Jin, GY Jung, N Chia, P-J Kim. Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis. (2017) Nat. Commun. 8, 15393
https://doi.org/10.1038/ncomms15393 -
Y Xiu, S Jang, JA Jones, NA Zill, RJ Linhardt, Q Yuan, GY Jung, MAG Koffas. Naringenin-responsive riboswitch-based fluorescent biosensor module for Escherichia coli co-cultures. (2017) Biotechnol. Bioeng. 114(10), 2235-2244
https://doi.org/10.1002/bit.26340 -
S Jang*, B Lee*, H-H Jeong, SH Jin, S Jang, SG Kim, GY Jung, C-S Lee. On-chip analysis, indexing and screening for chemical producing bacteria in microfluidic static droplet array. (2016) Lab Chip 16(10), 1909-1916 (* co-first authors)
https://doi.org/10.1039/C6LC00118A -
S Jang, J Yang, SW Seo, GY Jung. Riboselector: riboswitch-based synthetic selection device to expedite evolution of metabolite-producing microorganisms. (2015) Methods Enzymol. 550, 341-362
https://doi.org/10.1016/bs.mie.2014.10.039 -
SW Seo, J Yang, BE Min, S Jang, JH Lim, HG Lim, SC Kim, SY Kim, JH Jeong, GY Jung. Synthetic biology: Tools to design microbes for the production of chemicals and fuels. (2013) Biotechnol. Adv. 31(6), 811-817
https://doi.org/10.1016/j.biotechadv.2013.03.012 -
J Yang*, SW Seo*, S Jang, S-I Shin, CH Lim, T-Y Roh, GY Jung. Synthetic RNA devices to expedite the evolution of metabolite-producing microbes. (2013) Nat. Commun. 4, 1413
https://doi.org/10.1038/ncomms2404 -
J-S Yang*, SW Seo*, S Jang, GY Jung, S Kim. Rational engineering of enzyme allosteric regulation through sequence evolution analysis. (2012) PLoS Comput. Biol. 8(7), e1002612https://doi.org/10.1371/journal.pcbi.1002612